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Using a broad band, high parallelity and extremely high brilliance of synchrotron radiation x-rays a variety of medical imaging has been proposed. Two types of x-ray imaging systems using an angle analyzer (AA)crystal are popular now; one uses a Bragg type AA that was first proposed by Chapman et al who gave a name diffraction-enhanced imaging (DEI) ; the second one using a Laue type AA (LAA) was proposed by Ingal et al and by Chapman et al. In the Laue optics the condition of LAA thickness to produce a condition of x-ray dark-field imaging (DFI) was given. If a certain thickness of LAA was chosen the intensity of forward diffraction (FD) becomes zero at the just Bragg angle if LAA receives plane wave.
In 2000-2006 three papers of DEI-based CT (DEI-CT) imaging were presented. Later the concept of refraction-based tomosynthesis for sliced images was presented. At long last algorithm for DFI-based CT (DFI-CT) was proposed.
As a result we can say that a technique to visualize soft tissue for clinical and pathological diagnosis such as breast cancer and articular cartilage ex vivo is now ready with DFI, so that a variety of breast cancers and articular cartilage are under imaging. Furthermore this technique will be potentially extendable to all other cancers. All details including a potential prospect for clinical and pathological use will be presented in the seminar.
报告人简介:
Prof. Masami Ando is faculty of Research Institute for Science and Technology at Tokyo University of Science. He gained Doctor Degree of Engineering from University of Tokyo in 1974. And he got several Prizes during his research, including the prize from the Medical Imaging Society on "Development of K-edge Energy Subtraction TV System and Experiments" in 1993; Tsukuba Prize on "First Human Clinical Application of Angiography Using 2D Synchrotron Radiation" in 1997; Special Award from Horiba Co. Ltd. on “System Development for Early Diagnosis of Breast Cancer” in 2006. His research interest is the development of X-Ray Dark-Field Imaging for Clinical Use.